Endothelial stem cell

Definition : 

Endothelial stem cells (ESCs) are one of three types of stem cells found in bone marrow. They are multipotent, which describes the ability to give rise to many cell types, whereas a pluripotent stem cell can give rise to all types. ESCs have the characteristic properties of a stem cell: self-renewal and differentiation. These parent stem cells, ESCs, give rise to progenitor cells, which are intermediate stem cells that lose potency. Progenitor stem cells are committed to differentiating along a particular cell developmental pathway. ESCs will eventually produce endothelial cells (ECs), which create the thin-walled endothelium that lines the inner surface of blood vessels and lymphatic vessels.

1)  Sources

2) Properties

2.1 Self-renewal and differentiation

2.2 Blood vessel formation

2.3 Markers

3) Role in formation of vascular system

4) Role of insulin-like growth factors in endothelium     differentiation

5) Animal models of vasculogenesis

6) Role in recovery

7) Role in cancer

8)Future efforts