Mitosis is
the process by which a eukaryotic cell separates the chromosomes in its
cell nucleus into two identical sets in two nuclei. It is generally
followed immediately by cytokinesis, which divides the nuclei,
cytoplasm, organelles and cell membrane into two cells containing
roughly equal shares of these cellular components. Mitosis and
cytokinesis together define the mitotic (M) phase of the cell cycle -
the division of the mother cell into two daughter cells, genetically
identical to each other and to their parent cell. This accounts for
approximately 10% of the cell cycle.
Mitosis
occurs exclusively in eukaryotic cells, but occurs in different ways in
different species. For example, animals undergo an "open" mitosis,
where the nuclear envelope breaks down before the chromosomes separate,
while fungi such as Aspergillus nidulans and Saccharomyces cerevisiae
(yeast) undergo a "closed" mitosis, where chromosomes divide within an
intact cell nucleus. Prokaryotic cells, which lack a nucleus, divide by a process called binary fission.
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